Metabolic changes modify Treg cell function
نویسندگان
چکیده
منابع مشابه
Metabolic control of regulatory T cell (Treg) survival and function by Lkb1
The metabolic programs of functionally distinct T cell subsets are tailored to their immunologic activities. While quiescent T cells use oxidative phosphorylation (OXPHOS) for energy production, and effector T cells (Teffs) rely on glycolysis for proliferation, the distinct metabolic features of regulatory T cells (Tregs) are less well established. Here we show that the metabolic sensor LKB1 is...
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ژورنال
عنوان ژورنال: Nature Reviews Rheumatology
سال: 2016
ISSN: 1759-4790,1759-4804
DOI: 10.1038/nrrheum.2016.172